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Personal Care

Osmolality testing has unlimited applications in areas of personal care and hygiene.

Ensuring Product Safety

Products that come into contact with or penetrate the skin must have an osmolality within a physiological range to avoid damaging cells and tissues. In some instances, slightly hypo- or hyper-osmotic solutions are generated to promote wetting or drying effects.

Personal Care Product Testing

Osmolality has a wide range of applications for the manufacturing of skincare, personal lubricants, and optical products. For skincare and optical products, osmolality testing helps ensure that the product falls within the ideal osmolality range to either have a moisturizing or drying effect.

Osmolality impacts the effect and safety of personal lubricants. The World Health Organization (WHO) stated that the osmolality of these solutions should not exceed 1200 mOsm/kg, with this limit decreasing to a more iso-osmotic level in the future.


  • Aragona P et al. Physiochemical Properties of Hyaluronic Acid-Based Lubricant Eye Drops. Trans Vis Sci Tech. 2019;8(6):2.
  • Corrales R et al. Effects of Osmoprotectants on Hyperosmolar Stress in Cultured Human Corneal Epithelial Cells. Cornea 2008;27:574-579.
  • WHO/UNFPA/FHI, 2011-. Advisory Committee Notes to the Female Condom Technical Review Committee Meeting. [Geneva, Switzerland].

Have confidence in the personal care products produced for your customers with freezing point depression

The freezing point of a liquid (a solvent) is depressed when another compound is added, meaning that a solution has a lower freezing point than a pure solvent. Evaluating the freezing point depression of a sample can accurately measure the presence of all osmotically active substances in the sample.

Popular Educational Resources

Learn more about how osmolality can be utilized to help ensure quality and effectiveness of your personal care product by checking out our educational resources below





Associated Products

OsmoTECH® XT Single-Sample Micro-Osmometer

Best-in-class osmolality performance, designed for the toughest samples

OsmoTECH® PRO Multi-Sample Micro-Osmometer

Combines ease-of-use with accurate and precise measurements for reliable results


Bioprocessing Services

Get the best performance from your osmometer from the people who designed and built it. We provide a range of services and service plans to meet the different needs of our customers.

Our certified Field Service Engineers provide on-site professional support for the installation, training, validation, and maintenance of your osmometers.