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Process Development

Optimizing biologics process development with osmolality testing throughout development

Optimizing Your Development

Biopharmaceutical development and manufacturing involves many complex steps. Ensuring that these processes consistently produce a biopharmaceutical product of predetermined yield, purity, and quality is of utmost importance.

To optimize your manufacturing processes, osmolality can be used to monitor cell culture and fermentation to ensure optimal cell health, and consequently, high product quality and yield.

Ensuring Buffer Efficiency

Osmolality helps ensure that every step in your biologics process development is optimized. This helps provide precise buffer preparation and proves complete buffer exchange to improve purification efficiency while safeguarding your biologics as it passes through storage, reconstitution, and injection.

Optimize Cell Culture Conditions to Maximize Cell Density and Yield

When done right, osmolality, the measurement of total solute concentration, can help save time and money by delivering information throughout your biologics process development.

Excellent product and extremely efficient! Easy to clean and maintain. Excellent customer support and allows increased in-process testing capabilities.


Popular Educational Resources

Learn more about how our osmometers can be help streamline your biologics process development by checking out our educational resources below


An Insider’s Look: How One Parameter Can Optimize Key Phases of Bioprocessing Workflows


Osmolality as a concentration measurement method for key buffers in bioprocessing (Application Note)


Osmolality: A Predictor in Mammalian Cell Culture

Associated Products

OsmoTECH®HT Automated Micro-Osmometer

Automated high-throughput plate-based osmometer for cell line and process development

OsmoTECH®PRO Multi-Sample Micro-Osmometer

Combines ease-of-use with accurate and precise measurements for reliable results


Bioprocessing Services

Get the best performance from your osmometer from the people who designed and built it. We provide a range of services and service plans to meet the different needs of our customers.

Our certified Field Service Engineers provide on-site professional support for the installation, training, validation, and maintenance of your osmometers.